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TARTRATE-RESISTANT ACID PHOSPHATASE
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DeCS
Descriptor
English
:
Tartrate-Resistant Acid Phosphatase
Descriptor
Spanish
:
Fosfatasa Ácida Tartratorresistente
Descriptor
Portuguese
:
Fosfatase Ácida Resistente a Tartarato
Synonyms
English
:
AcPase V
Acid Phosphatase V
TRAP Type 5 AcPase
TRAcP
Tartrate-Resistant Acid Phosphatase Type 5
Type 5 Acid Phosphatase
Uteroferrin
Acid Phosphatase, Tartrate-Resistant
Phosphatase V, Acid
Phosphatase, Tartrate-Resistant Acid
Tartrate Resistant Acid Phosphatase
Tartrate Resistant Acid Phosphatase Type 5
V, AcPase
V, Acid Phosphatase
Tree Number:
D08.811.277.352.650.025.500
D08.811.277.352.650.625.862
Definition
English
:
One of several acid phosphatases in
humans
, other
mammals
,
plants
, and a few prokaryotes. The protein fold of
tartrate-resistant acid phosphatase
(TRAP) resembles that of the
catalytic domain
of plant purple
acid phosphatase
and other serine/threonine-protein phosphatases that also contain a metallophosphoesterase domain. One gene produces the various forms which include purple acid phosphatases from
spleen
and other
tissues
.
Tartrate-resistant acid phosphatase
is a biomarker for pathological states in which it is over-expressed. Such conditions include
GAUCHER DISEASE
;
HODGKIN DISEASE
;
BONE RESORPTION
; and
NEOPLASM METASTASIS.
History Note
English
:
2017 (1995)
Allowable Qualifiers
English
:
AD
administration & dosage
AE
adverse effects
AN
analysis
AI
antagonists & inhibitors
BI
biosynthesis
BL
blood
CF
cerebrospinal fluid
CS
chemical synthesis
CH
chemistry
CL
classification
CT
contraindications
DF
deficiency
DE
drug effects
EC
economics
GE
genetics
HI
history
IM
immunology
IP
isolation & purification
ME
metabolism
PK
pharmacokinetics
PD
pharmacology
PH
physiology
PO
poisoning
RE
radiation effects
SE
secretion
ST
standards
SD
supply & distribution
TU
therapeutic use
TO
toxicity
UL
ultrastructure
UR
urine
Record Number:
56474
Unique Identifier:
D000071681
Occurrence in VHL
:
Similar:
DeCS
CID-10
SciELO
LILACS
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